Deficiency of fatty acid-binding proteins in mice confers protection from development of experimental autoimmune encephalomyelitis

JM Reynolds, Q Liu, KC Brittingham, Y Liu… - The Journal of …, 2007 - journals.aai.org
… a protective role of FABP deficiency in the development of EAE and reveal altered APC
function of both macrophages and dendritic cell (DC) derived from FABP-deficient mice. …

[HTML][HTML] Targeting epidermal fatty acid binding protein for treatment of experimental autoimmune encephalomyelitis

E Rao, P Singh, Y Li, Y Zhang, YI Chi, J Suttles, B Li - BMC immunology, 2015 - Springer
… demonstrated that epidermal fatty acid binding protein (E-… responses in the mouse model
of experimental autoimmune … Furthermore, we have shown that CD4+ T cells deficient for E-…

[HTML][HTML] A novel fatty acid-binding protein 5 and 7 inhibitor ameliorates oligodendrocyte injury in multiple sclerosis mouse models

A Cheng, W Jia, I Kawahata, K Fukunaga - EBioMedicine, 2021 - thelancet.com
… ; targeted inhibition of the two proteins may confer potential therapeutic effects in MS … mouse
model (experimental autoimmune encephalomyelitis [EAE] mice), suggesting novel protein

[HTML][HTML] Fatty acid binding protein 4 promotes autoimmune diabetes by recruitment and activation of pancreatic islet macrophages

Y Xiao, L Shu, X Wu, Y Liu, LY Cheong, B Liao, X Xiao… - JCI insight, 2021 - ncbi.nlm.nih.gov
… Here we show that circulating fatty acid binding protein 4 (… autoimmune
encephalomyelitis/multiple sclerosis (19–21). FABP4-deficient mice exhibit a lower incidence of …

Combined adipocyte-macrophage fatty acidbinding protein deficiency improves metabolism, atherosclerosis, and survival in apolipoprotein E–deficient mice

JB Boord, K Maeda, L Makowski, VR Babaev, S Fazio… - Circulation, 2004 - Am Heart Assoc
deficiency would have an impact on longevity in 3KO mice. To evaluate this finding, we placed
male 3KO (n=13) and apoE −/− (n=12) mice … and mal1 deficiency conferring a significant …

Regulation of Th17 differentiation by epidermal fatty acid-binding protein

B Li, JM Reynolds, RD Stout, DA Bernlohr… - The Journal of …, 2009 - journals.aai.org
protection from development of experimental autoimmune … . Deficiency of fatty acid-binding
proteins in mice confers … the effector phase of experimental autoimmune encephalomyelitis. …

The Fabp5/calnexin complex is a prerequisite for sensitization of mice to experimental autoimmune encephalomyelitis

T Paskevicius, J Jung, M Pujol, P Eggleton… - The FASEB …, 2020 - Wiley Online Library
… -tail domain of Canx in conferring sensitivity to EAE induction, … protein (psoriasis-associated
fatty acid-binding protein [PA-… in epidermal-type fatty acid binding protein-deficient mice. J …

[引用][C] Deficiency of Fatty Acid-Binding Proteins in

GSH Gorgun, RD Stout, J Brittingham, Y Liu… - J Immunol, 2007

Fatty acid-binding protein E-FABP restricts tumor growth by promoting IFN-β responses in tumor-associated macrophages

Y Zhang, Y Sun, E Rao, F Yan, Q Li, Y Zhang… - Cancer research, 2014 - AACR
… Furthermore, E-FABP deficiency markedly increased E0771 … Because of the tumor protective
role of E-FABP in mouse … in the model of experimental autoimmune encephalomyelitis (8), …

Fatty acid binding protein (Fabp) 5 interacts with the calnexin cytoplasmic domain at the endoplasmic reticulum

J Jung, J Wang, J Groenendyk, D Lee… - Biochemical and …, 2017 - Elsevier
… of experimental autoimmune encephalomyelitis (EAE) … As Fabp5-deficient mice show protection
from the clinical … -tail domain may have an important role in conferring resistance to EAE. …